Opioid combination.
نویسندگان
چکیده
منابع مشابه
Polydrug abuse: a review of opioid and benzodiazepine combination use.
This paper reviews studies examining the pharmacological interactions and epidemiology of the combined use of opioids and benzodiazepines (BZDs). A search of English language publications from 1970 to 2012 was conducted using PubMed and PsycINFO(®). Our search found approximately 200 articles appropriate for inclusion in this paper. While numerous reports indicate that the co-abuse of opioids a...
متن کاملGabapentin and an opioid combination versus opioid alone for the management of neuropathic cancer pain: a randomized open trial.
Neuropathic cancer pain represents a major challenge. Treatment often requires adjuvant analgesics, including gabapentin, to complement the effects of opioids. This study aimed to compare the effectiveness and safety of gabapentin combined with an opioid versus opioid monotherapy for the management of neuropathic cancer pain. Seventy-five cancer patients who were receiving opioid therapy and re...
متن کاملA systematic review of combination step III opioid therapy in cancer pain: an EPCRC opioid guideline project.
BACKGROUND The use of combinations of opioids is a common clinical practice; however, this is not advocated by the World Health Organization (WHO) analgesic ladder. As opioid combination therapy becomes used increasingly, a review of the evidence on this practice was conducted. AIMS To carry out a systematic review of the use of strong opioids in combination in cancer pain. METHODS The foll...
متن کاملOpioid mechanisms and opioid drugs
C appreciate that there is interplay between the actions of the different subtypes of receptor and hence the value of drugs which target multiple receptor subtypes. Abstract The opioid system comprises four receptor subtypes: m (MOP), k (KOP), d (DOP), now called the ‘classical’ opioid receptors, and the ‘non classical’ nociceptin/orphanin FQ peptide (N/OFQ) receptor (NOP). Selective endogenous...
متن کاملMu Opioid Receptor Gene: New Point Mutations in Opioid Addicts
Introduction: Association between single-nucleotide polymorphisms (SNPs) in mu opioid receptor gene and drug addiction has been shown in various studies. Here, we have evaluated the existence of polymorphisms in exon 3 of this gene in Iranian population and investigated the possible association between these mutations and opioid addiction. Methods: 79 opioid-dependent subjects (55 males, 24...
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ژورنال
عنوان ژورنال: Współczesna Onkologia
سال: 2011
ISSN: 1428-2526
DOI: 10.5114/wo.2011.26449